Diabetes is not just a condition that affects humans. In fact, guinea pigs can also suffer from it. To understand this condition, it’s essential to grasp the basics of what diabetes is and how it affects your small pets.
What is diabetes?
Diabetes mellitus (type 2 diabetes) is a condition that arises when the body can’t use sugar efficiently. A guinea pig’s body relies on a hormone called insulin, produced by the pancreas, to use sugar as energy for its cells. However, sometimes, the pancreas doesn’t generate enough insulin. When this occurs, the cells can’t access the sugar they require and begin to use fat and protein from the body as alternative energy sources.
Symptoms of diabetes in guinea pigs
When a guinea pig has diabetes, a series of noticeable changes occur.
Weight Loss: Since the cells are using fat and protein for energy, the guinea pig starts to lose weight. This weight loss can be rapid and concerning.
Increased Thirst: Another major sign of diabetes is if you see your guinea pig frequently at the water bottle. When guinea pigs have high sugar levels in their blood, their kidneys have to work harder to create more urine to remove this excess sugar. This extra urine production can cause the guinea pig to lose more fluids, leading to dehydration. As a result, the guinea pig feels thirsty as its body signals the need to replenish the lost fluids by drinking more water.
Ketone Production: Another side effect of using fat as an energy source is the generation of waste products known as ketones. One specific ketone is acetone, which is expelled through the lungs when the guinea pig exhales. This can give their breath a distinctive acetone smell.
Lethargy: Your guinea pig might seem less active or more tired than usual.
It’s important to note that symptoms like increased thirst and weight loss are commonly seen in both diabetes and kidney disease. Additionally, there’s a connection between diabetes and kidney disease. The damage from having too much sugar in the blood can lead to kidney problems. High blood pressure, which often accompanies diabetes, can further strain the kidneys.
How to prevent diabetes in guinea pigs
Diet plays a pivotal role in preventing diabetes in guinea pigs. By ensuring proper nutrition and making informed food choices, you can reduce the risk for your pets. Here are some dietary guidelines:
- Increase hay intake. Always ensure a limitless supply of hay.
- Reduce sugar intake. Check the treats you provide to ensure they don’t have added sugars. Limit fruits and offer fewer vegetables high in sugar like sweetcorn and beetroot.
- Good quality pellets. Avoid muesli-type foods and any feed with added sugar.
- Focus on fresh food. The main part of their diet should consist of leafy green vegetables and herbs.

Diagnosis and treatment
Recognizing the symptoms is the first step, but confirming that a guinea pig has diabetes requires proper testing. Blood tests and urinalysis are essential to differentiate between diabetes and kidney disease. If these tests show high glucose levels, it’s indicative of diabetes.
While guinea pigs can recover from diabetes with a suitable diet, consulting a vet is crucial. They’ll likely suggest dietary adjustments (as mentioned in the prevention section) as the primary intervention rather than medication.
